Greetings,
I do not recommend using drugs to induce an astral experience unless you can astrally travel without drugs. Though it is true that they can enhance the effects, there are a plethora of ideas to consider first. e.g. Have you ever astrally traveled before? What was it like? Have you taken hallucinogens in the past? How did your body react to that? In short, the answer to your question is yes but before rushing into something such as this, do a good amount of research on the topic of astral travel and organic supplementation of it.
-Ashnook
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