Have you seen the work of Aubrey de Grey? He is working on the fringes of mainstream science but what he proposes is really quite reasonable, i.e. the first human beings to live to 1000 years are alive now, there is no one treatment that can extend life that long that will be developed over the next 30-40 years, but very likely one that will extend life a few decades. This will continue over the next few hundred years assuming no civilization doesn't collapse or technological regression, and people who keep up with new treatments will very likely live to be a thousand.
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